Colony-stimulating factors (CSFs) are secreted glycoproteins that bind to receptor proteins on the surfaces of hemopoietic stem cells, thereby activating intracellular signaling pathways that can cause the cells to proliferate and differentiate into a specific kind of blood cell (usually white blood cells. For red blood cell formation, see erythro...
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http://en.wikipedia.org/wiki/Colony-stimulating_factor
(from the article `blood`) ...correspond to red cells, phagocytic cells, and megakaryocytes. The formation of these individual colonies depends on hormonal sugar-containing ...
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http://www.britannica.com/eb/a-z/c/111
A substance that stimulates the production of blood cells. Colony-stimulating factors include granulocyte colony-stimulating factor (G-CSF), granulocyte-macrophage colony-stimulating factor (GM-CSF), and promegapoietin.
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http://www.cancer.gov/dictionary?expand=C
<cell biology> A glycoprotein growth factor that regulates the differentiation of particular cells. ... These substances act in either paracrine or autocrine fashion on marrow cells, appear to act synergistically and can exert actions on several lines of progenitor cells, and influence end cell function. These lymphokines induce the maturatio...
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http://www.encyclo.co.uk/local/20973
The drug given to autologous stem cell transplant patients before and during the harvest to increase the number of stem cells in the blood. It is also given to allogeneic donors to increase the number of cells in the circulating blood so they can be collected for transplant. Also called growth factor.
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http://www.encyclo.co.uk/local/22247
Cytokines involved in the maturation of various leucocyte, macrophage, monocyte lines.
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Colony-stimulating factor: A laboratory-made agent similar to a substance in the body that stimulates the production of blood cells. Treatment with colony-stimulating factors (CSFs) can help the blood- forming tissue recover from the effects of chemotherapy and radiation therapy. The CSFs include granulocyte colony-stimulating factors (G-CSF) and g...
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http://www.medterms.com/script/main/art.asp?articlekey=2793
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